As the oven hums and the aromatic scent of cinnamon wafts through my kitchen, it feels like a warm hug on a chilly evening. Today, I’m excited to share my take on Pastitsio Greek Lasagna, a comforting family-style meal that’s just as delightful for weeknight dinners as it is for special occasions. This layered beauty brings together a rich meat sauce, velvety béchamel, and perfectly cooked pasta, creating a dish that’s not just a feast for the eyes but also satiating for the soul. One of the best parts? You can prep it ahead of time, making it a fantastic make-ahead option for busy weeks. If you’re eager to explore a unique twist on traditional lasagna that’s sure to impress your loved ones, keep reading—this recipe promises to turn your kitchen into a Mediterranean haven! What is your favorite family comfort food?

Why is Pastitsio So Irresistible?
Comforting Layers: This dish is packed with rich flavors that hit all the right notes, making it the ultimate comfort food!
Easy Preparation: With straightforward steps, even novice cooks can master this delicious meal.
Make-Ahead Magic: Prep it a day in advance, refrigerate, and bake when you’re ready—a perfect solution for busy weeknights!
Versatile Ingredients: Feel free to swap in seasonal vegetables or leftover meats for a fresh twist. If you love Mediterranean flair, consider pairing it with a side of Greek Potato Salad for a perfect family feast.
Crowd-Pleasing Flavor: Each bite of Pastitsio is a warm hug that your family will crave, making it a fantastic centerpiece for gatherings!
Pastitsio Greek Lasagna Ingredients
For the Meat Sauce
• Ground Beef – The main protein source; ensure it’s well-drained after cooking to avoid a watery dish.
• Yellow Onion – Adds sweetness and depth to the sauce; shallots can be used for a milder flavor.
• Tomato Sauce – Provides moisture and acidity; canned or homemade both work well.
• Ground Cinnamon – Adds a warm, aromatic note; nutmeg can provide a similar warmth.
• Kosher Salt – Enhances overall flavor; adjust according to your taste preference.
For the Pasta Layer
• Pastitsio Noodles or Mostaccioli – The pasta base gives structure; cook just under al dente for the best results.
• Egg – Binds the noodles together; mixing thoroughly is essential for a cohesive layer.
For the Béchamel Sauce
• Unsalted Butter – Adds richness to the sauce; margarine can be used if preferred.
• All-Purpose Flour – Thickens the béchamel; gluten-free flour is an alternative for those with dietary restrictions.
• Whole Milk – Provides creaminess; low-fat milk works for a lighter version.
• Chicken Eggs – Enrich the béchamel and noodle mixture; ensure thorough mixing for a smooth texture.
For the Cheese Layer
• Kasseri Cheese – Traditional cheese gives authenticity; asiago or an Italian cheese blend can be substituted for similar flavor.
• Additional Cheese – Consider using more cheese for the topping for a deliciously ooey-gooey finish.
Step‑by‑Step Instructions for Pastitsio Greek Lasagna
Step 1: Prepare the Meat Sauce
Begin by heating a large skillet over medium heat. Add finely chopped yellow onion and sauté until it becomes translucent, about 5 minutes. Then, introduce one pound of ground beef, breaking it apart and browning it completely—aim for a nice golden color, approximately 10 minutes. Pour in tomato sauce and a sprinkle of ground cinnamon. Let the mixture simmer gently for 30 minutes, stirring occasionally, until flavors meld beautifully.
Step 2: Cook the Pasta
While the meat sauce simmers, bring a large pot of salted water to a boil. Add the pastitsio noodles or mostaccioli, cooking them until they are just under al dente, about 6-7 minutes. Drain the pasta, making sure to shake off excess moisture, and set it aside. In a mixing bowl, whisk together an egg and gently fold it into the drained pasta, ensuring an even coating.
Step 3: Make the Béchamel Sauce
In a medium saucepan, melt 4 tablespoons of unsalted butter over medium heat. Once melted, whisk in 1/4 cup of all-purpose flour, cooking for 1-2 minutes until lightly golden. Gradually add 2 cups of whole milk while continually whisking to avoid lumps. Cook this mixture until it thickens significantly, about 5 minutes, and then remove it from heat. Stir in two beaten eggs, mixing thoroughly for a silky texture.
Step 4: Assemble Layers
Preheat your oven to 350°F (175°C). In a greased 9×13-inch baking dish, layer half of the pasta mixture, followed by half of the meat sauce, and sprinkle with a generous layer of kasseri cheese. Repeat the layering process with the remaining pasta, meat sauce, and more cheese before spreading the comforting béchamel sauce over the top. Finish with an additional sprinkle of cheese for that golden crust.
Step 5: Bake to Perfection
Carefully place the baking dish into the preheated oven. Bake the Pastitsio Greek Lasagna for about 1 hour, until the top is bubbly and golden brown. For an extra crispy topping, switch to broil for an additional 2-3 minutes, watching closely to prevent burning. The delightful aroma will surely fill your kitchen as it bakes.
Step 6: Rest Before Serving
Once baked to perfection, take the Pastitsio out of the oven and allow it to rest for 10-30 minutes. This step is crucial for the layers to set, making slicing neat and easy. As it cools, the flavors will deepen, resulting in a better tasting experience when you finally serve this delicious comfort food.

How to Store and Freeze Pastitsio Greek Lasagna
Fridge: Store leftover pastitsio tightly covered in the fridge for up to 4 days to maintain its delicious flavor and moisture.
Freezer: Freeze portions of pastitsio in airtight containers or wrap it tightly in foil for up to 3 months. This makes for an easy meal option later on!
Reheating: Thaw overnight in the fridge and reheat in the oven at 350°F until heated through, about 20-30 minutes, for the best texture.
Make-Ahead Magic: As a make-ahead option, pre-assemble the pastitsio and refrigerate, then bake it fresh when you’re ready to enjoy this delightful Greek lasagna.
Variations & Substitutions for Pastitsio Greek Lasagna
Feel free to personalize this dish to fit your tastes and dietary needs, creating a unique twist on a classic favorite!
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Vegetarian Option: Swap ground beef for a blend of mushrooms and lentils for a hearty and nutritious filling. The earthy flavors provide a satisfying alternative, making it a favorite for non-meat eaters.
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Gluten-Free: Use gluten-free pasta and a certified gluten-free flour for the béchamel to enjoy this beloved dish worry-free. It’s a great way to share this family classic without compromising on taste.
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Dairy-Free: Substitute the cheese with a dairy-free alternative and use almond or oat milk for the béchamel. You won’t miss the dairy, as the other flavors still shine beautifully.
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Extra Veggies: Mix in spinach, zucchini, or roasted red peppers into the meat sauce for added nutrition and a pop of color. This twist not only enhances flavor but also makes the dish even more wholesome.
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Heat Level: For a spicy kick, add crushed red pepper flakes or diced jalapeños into the meat sauce. The added heat can turn up the excitement in every bite, perfect for those who enjoy a little zing!
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Nutty Flavor: Incorporate pine nuts or walnuts into the meat mixture for added texture and a nutty undertone that complements the cinnamon perfectly.
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Cheesy Delight: Mix layers of different cheeses like feta, mozzarella, or gouda for a rich, complex flavor profile. The more cheese, the merrier!
If you love Mediterranean sides, consider serving this with a refreshing Greek Potato Salad for a complete meal that will have everyone asking for seconds. Enjoy experimenting with these variations!
What to Serve with Authentic Greek Pastitsio Lasagna
There’s nothing quite like a hearty platter of Mediterranean flavors to accompany your pastitsio, creating a delightful family feast!
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Fresh Greek Salad: Crisp tomatoes, cucumbers, and feta add a refreshing contrast to the creamy pastitsio.
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Warm Pita Bread: The perfect vessel for scooping up bites of pastitsio, enhancing every mouthful with warmth and texture.
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Roasted Vegetables: Seasonal veggies like zucchini and bell peppers bring brightness and a touch of sweetness, balancing the rich meat sauce.
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Ouzo or Retsina Wine: A splash of these traditional Greek drinks elevates the meal, bringing a sophisticated twist to your dining experience.
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Lemon Rice Pilaf: Fluffy rice infused with lemon zest adds a light, zesty touch that complements the rich layers of pastitsio.
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Baklava for Dessert: End your meal with this sweet, nutty pastry; its honeyed layers are a delightful way to round off the evening.
Expert Tips for Pastitsio Greek Lasagna
Drain Meat Well: Ensure the ground beef is well-drained after cooking to prevent a watery pastitsio that loses its delightful texture.
Pasta Perfection: Don’t overcook the pasta; it should be just under al dente since it will continue cooking in the oven during baking.
Smooth Béchamel: Allow the béchamel sauce to rest briefly before mixing in the eggs. This helps achieve a smooth and creamy consistency.
Resting Period: Let the pastitsio cool for at least 10–30 minutes after baking for easier slicing and enhanced flavor melding.
Layering Tips: When layering, be generous with cheese and béchamel sauce to create that heavenly creamy topping you crave in a pastitsio Greek lasagna!
Make Ahead Options
These Pastitsio Greek Lasagna are ideal for busy weeknights and meal prep! You can prepare the meat sauce and béchamel sauce up to 24 hours in advance; simply refrigerate them tightly covered to maintain freshness. You can also layer the cooked pastitsio noodles with the meat sauce and cheeses and refrigerate the assembled dish overnight. When you’re ready to serve, just pop it into a preheated oven at 350°F (175°C) and bake for about 1 hour. For best results, allow the lasagna to rest for 10-30 minutes after baking to achieve clean slices. With these make-ahead options, enjoy a homemade meal that tastes just as delicious as if it were freshly made!

Pastitsio Greek Lasagna Recipe FAQs
What type of ground beef should I use for pastitsio?
For the best flavor and texture, use lean ground beef. It’s important to ensure it’s well-drained after cooking to prevent a watery dish. If you prefer a richer flavor, you can even use a blend of ground beef and ground lamb for a traditional twist!
How long can I store leftover pastitsio in the fridge?
Leftover pastitsio can be stored tightly covered in the refrigerator for up to 4 days. Make sure it’s well-sealed to maintain its moisture and flavor. If you’re a fan of meal prep, this is a fantastic option for quick meals throughout the week!
Can I freeze pastitsio? If so, how?
Absolutely! You can freeze pastitsio for up to 3 months. I recommend cutting it into serving-sized portions and wrapping them tightly in plastic wrap, then placing them in airtight containers. When you’re ready to enjoy, thaw overnight in the fridge, and reheat in a preheated oven at 350°F for about 20-30 minutes for the best texture.
What if my béchamel sauce turns lumpy?
Don’t worry! If your béchamel ends up lumpy, you can easily fix it by whisking vigorously while it cooks. If it remains lumpy after adding the eggs, try using an immersion blender to smooth it out. For future batches, remember to add the milk slowly while whisking constantly to prevent lumps from forming.
Is pastitsio suitable for people with certain dietary restrictions?
Yes! You can easily customize pastitsio to accommodate dietary needs. For a gluten-free version, use gluten-free pasta and flour for the béchamel. If you have dairy allergies, consider using plant-based milk and cheese alternatives. Just be sure to check the labels for any hidden ingredients. It’s a wonderfully versatile dish!
Can I make pastitsio ahead of time?
Definitely! One of the best things about pastitsio is that it can be prepared in advance. Simply assemble the dish completely, cover it tightly, and refrigerate it for up to 24 hours before baking. When you’re ready, pop it into the oven for a warm, welcoming family meal without any last-minute fuss!

Delicious Pastitsio Greek Lasagna You’ll Make Again and Again
Ingredients
Equipment
Method
- Heat a large skillet over medium heat. Sauté finely chopped onion until translucent, about 5 minutes.
- Add ground beef, breaking it apart and browning for about 10 minutes until golden.
- Pour in tomato sauce and a sprinkle of ground cinnamon, letting the mixture simmer for 30 minutes.
- Bring a large pot of salted water to a boil and cook pastitsio noodles until just under al dente, about 6-7 minutes. Drain and set aside.
- Whisk together an egg and fold it into the drained pasta for an even coating.
- In a medium saucepan, melt butter, whisk in flour, then gradually add milk, cooking until thickened.
- Remove from heat and stir in two beaten eggs for a silky texture.
- Preheat the oven to 350°F. Layer half of the pasta, half of the meat sauce, and sprinkle kasseri cheese.
- Repeat layers with remaining pasta, meat sauce, and more cheese, then spread béchamel over the top.
- Bake for about 1 hour until bubbly and golden brown, switching to broil for 2-3 minutes if desired.
- Rest for 10-30 minutes before slicing for neat portions.

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